Acetyl-L-Carnitine Hydrochloride

**Semantic type:** Pharmacologic Substance

**Definition:** A nutritional supplement composed of the hydrochloride salt form of the acetylated form of the endogenously produced L-carnitine, with potential neuroprotective, cognitive-enhancing, anti-depressive and immunomodulating activities. L-carnitine is responsible for the transport of fatty acids into the mitochondria for breakdown. It may also relieve peripheral neuropathy induced by chemotherapy, diabetes or other diseases. In addition, acetyl-L-carnitine may modulate the immune response by increasing T-lymphocytes maturation and may downregulate pro-inflammatory cytokines in response to viruses, such as SARS-CoV-2. It may also disrupt the ACE2 signaling pathway and inhibit the production of reactive oxygen species (ROS).

**Synonyms:** - 1-Propanaminium, 2-(acetyloxy)-3-carboxy-N,N,N-trimethyl-, chloride, (R)- - Acetylcarnitine Hydrochloride, L- - Acetylcarnitine L-form HCl - LEVACECARNINE HYDROCHLORIDE - acetyl-L-carnitine hydrochloride - o-Acetyl-L-carnitine hydrochloride