Apraclonidine

**Semantic type:** Pharmacologic Substance

**Definition:** A clonidine derivative with selective alpha-2-adrenergic agonistic activity. Upon ocular administration, apraclonidine enhances aqueous humor uveoscleral outflow and decreases aqueous production by vasoconstriction. This may decrease intraocular pressure (IOP).

**Synonyms:** - APRACLONIDINE - p-Aminoclonidine