Chlorpheniramine Polistirex

**Semantic type:** Pharmacologic Substance

**Definition:** A complex of the synthetic alkylamine derivative and histamine-1 (H1) receptor antagonist chlorpheniramine with sulfonated styrene-divinylbenzene copolymer, with anti-allergic activity. Upon administration, chlorpheniramine competitively blocks the H1 receptor, thereby preventing the actions of histamine on capillaries, and the resulting vasodilation and edema of the respiratory mucosa. Chlorpheniramine also displays anticholinergic and mild sedative effects.

**Synonyms:** - 3-(p-Chlorophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine - 4-Chloropheniramine - Allergican - Allergisan - CHLORPHENIRAMINE - Chloropheniramine - Chlorophenylpyridamine - Chloropiril - Chlorphenamine - Chlorpheniramine - Chlorpheniramine - Chlorprophenpyridamine - Haynon - Hayon - Histadur - Polaronil