Corticorelin Ovine

**Semantic type:** Pharmacologic Substance

**Definition:** A recombinant ovine corticotropin-releasing hormone (CRH), a 41 amino acids peptide similar to human CRH, used as a diagnostic agent. Corticorelin ovine is a potent stimulator of adrenocorticotropic hormone (ACTH), secreted from the anterior pituitary gland. In turn, ACTH stimulates cortisol production from the adrenal cortex and is regulated by a negative feedback mechanism. Corticorelin ovine triflutate is used as a diagnostic tool in differentiating pituitary and ectopic production of ACTH.

**Synonyms:** - CORTICORELIN OVINE