Dinoprostone

**Semantic type:** Pharmacologic Substance

**Definition:** A synthetic prostaglandin E2 (PGE2) analogue with smooth muscle contraction inducing property. It has been suggested that PGE2 regulates the intracellular levels of cyclic 3, 5-adenosine monophosphate (cAMP) by activating adenylate cyclase and thereby increases cellular membrane calcium ion transport. By acting directly on the myometrium, dinoprostone induces uterine and gastrointestinal smooth muscle contractions.

**Synonyms:** - Cervidil - DINOPROSTONE - Dinoglandin - Enzaprost E - Minprostin E2 - Prepidil - Prostin E2