Monoethanolamine

**Semantic type:** Pharmacologic Substance

**Definition:** A first generation monoethanolamine with antihistaminic property. Ethanolamine competes with free histamine for binding at the histamine (H)-1 receptor thereby acting as an inverse agonist that combines with and stabilizes the inactive form of the H1-receptor thereby shifting the equilibrium toward the inactive state. This leads to a reduction of the negative symptoms brought on by H1-receptor binding.

**Synonyms:** - 1-Amino-2-hydroxyethane - 2-AMINOETHANOL - 2-Amino-1-ethanol - Colamine - Ethanolamine - Olamine - Thiofaco M-50 - beta-Aminoethyl Alcohol - beta-Hydroxyethylamine