Bupropion

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** An aminoketone with antidepressant activity. The molecular mechanism of the antidepressant effect of bupropion is unknown. This agent does not inhibit monoamine oxidase and, compared to classical tricyclic antidepressants, is a weak blocker of the neuronal uptake of serotonin and norepinephrine. Buproprion also weakly inhibits the neuronal re-uptake of dopamine.

**Synonyms:** - 1-Propanone, 1-(3-Chlorophenyl)-2-((1,1-dimethylethyl)amino)- - Amfebutamon - BUPROPION - bupropion