Dextromethorphan

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex.

**Synonyms:** - DEXTROMETHORPHAN - DXM