Diphenoxylate

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A piperidine derivate, chemically related to narcotic meperidine with antidiarrheal activity and devoid of central nervous system (CNS) activity. Diphenoxylate acts on opioid receptors in the gastrointestinal tract, thereby decreasing gastrointestinal motility and causing constipation or preventing diarrhea.

**Synonyms:** - DIPHENOXYLATE