Attenuated Listeria monocytogenes ANZ-100

**Semantic type:** Bacterium|Pharmacologic Substance

**Definition:** A live-attenuated strain of the Gram-positive bacterium Listeria monocytogenes (Lm) with potential immunostimulatory and antineoplastic activities. Upon intravenous administration, attenuated Listeria monocytogenes ANZ-100 may accumulate in and infect liver cells where it may activate a potent innate immune response and an adaptive immune response involving the by recruitment and activation of T lymphocytes. This agent may potentiate the immune response to vaccines against various liver neoplasms.

**Synonyms:** - ANZ 100 - ANZ-100 - ANZ-100 - ANZ100 - CRS-100