Methacarn

**Semantic type:** Indicator, Reagent, or Diagnostic Aid|Organic Chemical

**Definition:** A liquid preservative for cytological materials, consisting of methanol, chloroform and glacial acetic acid in a 6:3:1 ratio. It is typically used on tissues to be paraffin-embedded and immunochemically stained and is useful for the preservation of nucleic acids in situ.

**Synonyms:** - Methanol-Carnoy - Methanol-substituted Carnoy's Solution