FOLFIRI Regimen

**Semantic type:** Therapeutic or Preventive Procedure

**Definition:** A regimen consisting of leucovorin calcium (calcium folinate), 5-fluorouracil, and irinotecan that can be used in the treatment of ampullary, appendiceal, small bowel, pancreatic and occult primary adenocarcinoma; colorectal, esophageal and esophagogastric junction, gastric, and hepatobiliary cancers; well-differentiated grade 3 neuroendocrine tumors (NETs), and extrapulmonary poorly differentiated neuroendocrine carcinoma, large or small cell carcinoma and mixed neuroendocrine-non-neuroendocrine neoplasm.

**Synonyms:** - FOLFIRI - FOLFIRI - FOLFIRI (L-Leucovorin) - FOLFIRI regimen - Fluorouracil Continuous Infusion/Leucovorin/Irinotecan - Fluorouracil-Folinic Acid-Irinotecan - Fluorouracil/Folinic Acid/Irinotecan - Fluorouracil/Leucovorin/Irinotecan - Folinic Acid-Fluorouracil-Irinotecan Regimen - Folinic Acid/Fluorouracil/Irinotecan Regimen