LMB-86 Regimen

**Semantic type:** Therapeutic or Preventive Procedure

**Definition:** A regimen consisting of five phases used for the treatment of adult L3 acute lymphoblastic leukemia (ALL3 or Burkitt's type) and for adult Burkitt's lymphoma. The five phases include: cytoreduction, induction given as two consecutive courses, consolidation and maintenance. This particular regimen differs from other LMB/SFOP (B-cell non-Hodgkin lymphoma and B-ALL/Societe Francaise Oncologie Pediatrique) protocols to reflect the treatment of central nervous system (CNS) disease using high dose methotrexate, high dose cytarabine, intrathecal therapy and cranial irradiation. The LMB 89 Group C regimen follows a similar regimen to that outlined in the LMB 86 protocol.

**Synonyms:** - LMB-89 Group C