Magrath Regimen

**Semantic type:** Therapeutic or Preventive Procedure

**Definition:** A regimen consisting of cyclophosphamide, vincristine, doxorubicin, prednisone, and high-dose methotrexate used to treat aggressive forms of non-Hodgkin lymphoma; also used as primary treatment of AIDS-related and high-risk Burkitt's lymphoma. Intrathecal cytarabine and methotrexate are included in this regimen as either prophylaxis or treatment for central nervous system (CNS) involvement.

**Synonyms:** - Magrath Protocol