ARACNE Algorithm

**Semantic type:** Intellectual Product

**Definition:** An information-theoretic algorithm for reverse engineering of transcriptional networks using microarray data, specifically designed to scale up to the complexity of regulatory networks in mammalian cells, yet general enough to address a wider range of network deconvolution problems, while eliminating the majority of indirect interactions inferred by co-expression methods.

**Synonyms:** - Algorithm for the Reconstruction of Accurate Cellular Networks