Tenosynovial Giant Cell Tumor, Localized Type

**Semantic type:** Neoplastic Process

**Definition:** A well-circumscribed, lobulated tumor, completely or partially covered by a fibrous capsule. It usually arises in the fingers. It is characterized by the presence of mononuclear cells, multinucleated osteoclast-like giant cells, hemosiderin-laden macrophages, foam cells, and an inflammatory infiltrate. The tumor is slow-growing, usually developing over several years. Clinical presentation includes painless edema of the affected site.

**Synonyms:** - Localized Giant Cell Neoplasm of Tendon Sheath - Localized Giant Cell Neoplasm of Tenosynovium - Localized Giant Cell Neoplasm of the Tenosynovium - Localized Giant Cell Tumor of Tendon Sheath - Localized Giant Cell Tumor of Tenosynovium - Localized Giant Cell Tumor of the Tenosynovium - Localized Tenosynovial Giant Cell Neoplasm - Localized Tenosynovial Giant Cell Tumor - Nodular Tenosynovitis