Etilefrine

**Semantic type:** Pharmacologic Substance

**Definition:** An adrenergic agonist with vasoconstrictive activity. Etilefrine selectively binds to and activates alpha-1-adrenergic receptors of the arteriolar and venous vasculature. This causes smooth muscle contraction and leads to a decrease in venous pooling and increase in blood pressure. This agent may also stimulate beta-1 adrenergic receptors, leading to positive chronotropic and inotropic effects.

**Synonyms:** - Apha-((ethylamino)methyl)-3-hydroxybenzenemethanol - ETILEFRINE - S 40032