Glycoprotein Hormones Alpha Polypeptide

**Semantic type:** Pharmacologic Substance

**Definition:** The alpha polypeptide chain of any of the four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle-stimulating hormone (FSH), and thyroid-stimulating hormone (TSH). Overexpressed in certain estrogen receptor (ER)-positive cancers, glycoprotein hormones alpha polypeptide (choriogonadotropin alpha; CGA) may be used as a biomarker for these types of cancer or as a predictor for the responsiveness of certain anti-estrogen therapy.

**Synonyms:** - Anterior Pituitary Glycoprotein Hormones Common Alpha Subunit - CG-alpha - Choriogonadotropin Alpha Chain - Chorionic Gonadotrophin Alpha Subunit - FSH-alpha - Follicle-Stimulating Hormone Alpha Chain - GLYCOPROTEIN HORMONES ALPHA POLYPEPTIDE - LSH-alpha - Luteinizing Hormone Alpha Chain - Luteinizing Hormone Subunit Alpha - Lutropin Alpha Chain - TSH-alpha - Thyroid-Stimulating Hormone Alpha Chain - Thyrotropin Alpha Chain