Hydroxystilbamidine Isethionate

**Semantic type:** Pharmacologic Substance

**Definition:** The isethionate salt form of hydroxystilbamidine, a cationic dye with antifungal, antitrypanosomal, antimalarial, and carcinostatic activities. Hydroxystilbamidine is able to bind to DNA and RNA in a non-intercalating manner, and is a powerful inhibitor of ribonucleases, thereby impeding cellular processes in protozoa. This agent was also shown to bind to lysosomes and induced a large number of lysosome-like bodies and secretion granules in trypanosome.

**Synonyms:** - HYDROXYSTILBAMIDINE DIISETHIONATE