Medronic Acid

**Semantic type:** Pharmacologic Substance

**Definition:** A methylene-substituted bisphosphonate. Medronic acid has affinity for and adheres to the surface of hydroxyapatite crystals in the bone matrix. This agent accumulates at sites of osteoid mineralization and can be used, complexed with radioisotopes such as technetium 99m, in bone imaging.

**Synonyms:** - MEDRONIC ACID - Methylene Diphosphonate - Methylenediphosphonic Acid