Levomepromazine

**Semantic type:** Pharmacologic Substance

**Definition:** A phenothiazine and typical antipsychotic agent, with sedative/hypnotic, anxiolytic, antiemetic, analgesic and antipsychotic activities. Although the exact mechanism of action of levomepromazine is not fully known, upon administration, this agent appears to act as an antagonist for a variety of receptors in the central nervous system (CNS), including adrenergic, dopamine, histamine, cholinergic and serotonin (5-hydroxytryptamine; 5-HT) receptors. Blocking these receptors results in levomepromazine's pharmacologic effects.

**Synonyms:** - (-)-10-(3-(Dimethylamino)-2-methylpropyl)-2-methoxyphenothiazine - Arc-VI-C-5 - Bayer 1213 - LEVOMEPROMAZINE - Levoprome - Methotrimeprazine - Neozine - Nirvan - Nozinan