Ampulla of Vater Small Cell Neuroendocrine Carcinoma

**Semantic type:** Neoplastic Process

**Definition:** An aggressive high-grade carcinoma with neuroendocrine differentiation that arises from the ampulla of Vater and is composed of malignant small cells. The mitotic count is more than 20 per 2 mm2 and/or the Ki-67 index is more than 20%.

**Synonyms:** - Ampulla of Vater Small Cell Carcinoma - Ampulla of Vater Small Cell NEC - Ampullary Small Cell Carcinoma - Small Cell Neuroendocrine Carcinoma of the Ampullary Region