Crohn Disease-Like Reaction

**Semantic type:** Finding

**Definition:** A distinctive Crohn's disease-like reaction (CLR) consisting of discrete lymphoid aggregates, some with germinal centers, and surrounding stellate fibrosis commonly found around colorectal adenocarcinomas in the absence of clinical or pathologic evidence of prior Crohn's disease.

**Synonyms:** - CLR - Crohn disease-like reaction - Crohn's Disease-Like Reaction - Crohn's-Like Lymphoid Reaction - Crohn-Like Reaction - Crohn-like reaction