N-Telopeptide

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** This polypeptide is comprised of the amino terminal portions of fibrillar collagen, which are not part of the triple helical structure. Bone resorption of type I collagen by osteoclasts results in the release of this peptide. Thus, this polypeptide is utilized as a biomarker for bone loss.

**Synonyms:** - Collagen Cross-Linked N-Telopeptide - N-Terminal Type I Collagen Cross-Linked - NTx - Type I Collagen Cross-Linked N-Telopeptide