MBL2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MBL2 wild-type allele is located within 10q11.2-q21 and is approximately 6 kb in length. This allele, which encodes mannose-binding protein C, is involved in pathogen immune response initiation through activation of the complement pathway. Polymorphisms in the allele may increase the risk for colon cancer.

**Synonyms:** - COLEC1 - HSMBPC - MBL - MBP - MBP1 - MGC116832 - MGC116833 - Mannose-Binding Lectin (Protein C) 2, Soluble (Opsonic Defect) wt Allele