Primary Cutaneous Anaplastic Large Cell Lymphoma

**Semantic type:** Neoplastic Process

**Definition:** An anaplastic large cell lymphoma limited to the skin at the time of diagnosis. Most patients present with solitary or localized skin lesions, which may be tumors, nodules or papules. The t(2;5) translocation that is present in many cases of systemic anaplastic large cell lymphoma, is not found in this disease. (WHO, 2001)

**Synonyms:** - ALCL, cutaneous - Anaplastic large-cell lymphoma, primary cutaneous type - C-ALCL - Primary Anaplastic Large Cell Lymphoma of Skin - Primary Anaplastic Large Cell Lymphoma of the Skin - Primary Cutaneous CD30 Positive Anaplastic Large Cell Lymphoma - Primary Cutaneous CD30+ ALCL - Primary Cutaneous CD30+ Anaplastic Large Cell Lymphoma - Primary cutaneous anaplastic large cell lymphoma