Childhood B Acute Lymphoblastic Leukemia with t(9;22)(q34.1;q11.2); BCR-ABL1

**Semantic type:** Neoplastic Process

**Definition:** A B acute lymphoblastic leukemia that occurs during childhood. It is characterized by the presence of lymphoblasts that carry a translocation between the BCR gene on chromosome 22 and the ABL1 gene on chromosome 9. It results in the production of the p190 kd or p210 kd fusion protein. It has an unfavorable clinical outcome.

**Synonyms:** - B Acute Lymphoblastic Leukemia with t(9;22)(q34.1;q11.2); BCR-ABL1 - Childhood B Acute Lymphoblastic Leukemia with t(9;22)(q34.1;q11.2); BCR::ABL1 - Childhood B Acute Lymphoblastic Leukemia with t(9;22)(q34;q11.2); BCR-ABL1 - Childhood B Acute Lymphoblastic Leukemia with t(9;22)(q34;q11.2); BCR-ABL1 - Childhood B-Cell Acute Lymphoblastic Leukemia with t(9;22)(q34;q11.2); BCR-ABL1 - Philadelphia Positive Childhood Acute Lymphoblastic Leukemia - Philadelphia Positive Childhood Precursor Lymphoblastic Leukemia - Philadelphia-Positive ALL