Myelodysplastic Syndrome with del(5q)

**Semantic type:** Neoplastic Process

**Definition:** A myelodysplastic syndrome characterized by a deletion between bands q31 and 33 on chromosome 5. The number of blasts in the bone marrow and blood is <5%. The bone marrow is usually hypercellular or normocellular with increased number of often hypolobated megakaryocytes. The peripheral blood shows macrocytic anemia. This syndrome occurs predominantly but not exclusively in middle age to older women. The prognosis is good and transformation to acute leukemia is rare. (WHO, 2001)

**Synonyms:** - 5Q minus syndrome - 5Q- syndrome - 5q- Syndrome - MDS-del(5q) - Myelodysplastic Neoplasm with Low Blasts and 5q Deletion - Myelodysplastic Syndrome Associated with Isolated del (5q) Chromosome Abnormality - Myelodysplastic Syndrome with 5q Deletion - Myelodysplastic Syndrome with Isolated Del (5Q) - Myelodysplastic Syndrome with Isolated del(5q) - Myelodysplastic Syndrome with Isolated del(5q) - Myelodysplastic Syndrome with Isolated del(5q) - Myelodysplastic Syndrome with Isolated del(5q) - Myelodysplastic syndrome with 5q deletion (5q-) syndrome - Myelodysplastic syndrome with isolated del (5q) - Myelodysplastic syndrome with isolated del (5q) chromosomal abnormality