von Willebrand Disease

**Semantic type:** Disease or Syndrome

**Definition:** Hereditary or acquired coagulation disorder characterized by a qualitative or quantitative deficiency of the von Willebrand factor. The latter plays an important role in platelet adhesion. Signs and symptoms include bruises, nose bleeding, gum bleeding following a dental procedure, heavy menstrual bleeding, and gastrointestinal bleeding.

**Synonyms:** - Von Willebrand's disease - von Willebrand Disorder - von Willebrand's Disease