ALOX5 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ALOX5 wild-type allele is located in the vicinity of 10q11.2 and is approximately 72 kb in length. This allele, which encodes arachidonate 5-lipoxygenase protein, is involved in the regulation of leukotriene signaling. Mutations in the gene, which affect the enzymatic activity of the gene product, play a role in asthma, atherosclerosis and several cancers.

**Synonyms:** - 5-LO - 5LPG - Arachidonate 5-Lipoxygenase wt Allele - LOG5 - MGC163204 - RP11-67C2.3