Arachidonate 5-Lipoxygenase

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Arachidonate 5-lipoxygenase protein (674 aa, ~78 kDa) is encoded by the human ALOX5 gene. This protein plays a role in the synthesis of leukotrienes from arachidonic acid; thus, it mediates both inflammation and allergen responses.

**Synonyms:** - 5-LO - 5-Lipoxygenase - 5LOX - ALOX5 - EC 1.13.11.34