IL21R wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human IL21R wild-type allele is located in the vicinity of 16p11 and is approximately 48 kb in length. This allele, which encodes interleukin-21 receptor protein, is involved in the regulation of cytokine signaling. A translocation t(3;7)(q27;p12) that fuses the gene to the BCL6 gene is implicated in diffuse large B-cell lymphomas.

**Synonyms:** - CD360 - IL21R - IMD56 - Interleukin 21 Receptor wt Allele - NILR - UNQ3121/PRO10273