Barrett Adenocarcinoma

**Semantic type:** Neoplastic Process

**Definition:** An adenocarcinoma arising from Barrett metaplastic epithelium in the esophagus. There is evidence supporting the idea that the Barrett adenocarcinomas develop through a stepwise progression through intestinal metaplastic epithelium to epithelial dysplasia to malignancy. Adenocarcinomas arising in the setting of Barrett esophagus are typically papillary and/or tubular. In terms of grading, they are well or moderately differentiated adenocarcinomas.

**Synonyms:** - Adenocarcinoma Arising in Barrett's Mucosa - Barrett's Adenocarcinoma