Aurora Kinase Inhibitor SNS-314

**Semantic type:** Pharmacologic Substance

**Definition:** A synthetic small molecule Aurora kinase (AK) inhibitor with potential antineoplastic activity. Aurora kinase inhibitor SNS-314 selectively binds to and inhibits AKs A and B, which may result in the inhibition of cellular division and proliferation in tumor cells that overexpress AKs. AKs are serine-threonine kinases that play essential roles in mitotic checkpoint control during mitosis.

**Synonyms:** - SNS-314 - SNS-314