Paget Disease

**Semantic type:** Neoplastic Process

**Definition:** A malignant neoplasm composed of large cells with large nuclei, prominent nucleoli, and abundant pale cytoplasm (Paget cells). Paget cell neoplasms include Paget disease of the nipple and extramammary Paget disease which may affect the vulva, penis, anus, skin and scrotum.

**Synonyms:** - Paget Cell Neoplasm - Paget's Cell Neoplasm - Paget's Disease