Nadofaragene Firadenovec

**Semantic type:** Pharmacologic Substance

**Definition:** A replication-deficient recombinant adenovirus encoding human interferon alpha-2b with potential antineoplastic activity. Upon intravesical administration, nadofaragene firadenovec infects nearby tumor cells and expresses INF alpha-2b intracellularly which activates the transcription and translation of genes whose products mediate antiviral, antiproliferative, antitumor, and immune-modulating effects.

**Synonyms:** - Adstiladrin - Instiladrin - NADOFARAGENE FIRADENOVEC - Nadofaragene Firadenovec-vncg - Nadofaragene Firadenovec/Syn3 - Nadofaragene Firadenovec/Syn3 - Nadofaragene firadenovec - Recombinant Adenovirus-Interferon SCH 721015 - Recombinant Adenovirus-Interferon With Syn3 - Recombinant Adenovirus-Interferon/Syn3 - SCH 721015 - SCH-721015 - SCH721015 - TR 002 - TR-002 - TR002 - rAd-IFN - rAd-IFN-2b - rAd-IFN/Syn3