MUC16 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MUC16 wild-type allele is located in the vicinity of 19q13.2 and is approximately 132 kb in length. This allele, which encodes mucin-16 protein, may play a role in the mediation of both cell adhesion and mucosal surface structural integrity. The gene is expressed aberrantly at elevated levels in ovarian cancers.

**Synonyms:** - CA125 - FLJ14303 - Mucin 16, Cell Surface Associated wt Allele