Nabiximols

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** An herbal preparation containing a defined quantity of specific cannabinoids formulated for oromucosal spray administration with potential analgesic activity. Nabiximols contains a standardized extract of tetrahydrocannabinol (THC), the non-psychoactive cannabinoid cannabidiol (CBD), other minor cannabinoids, flavonoids, and terpenes from two cannabis plant varieties. Cannabinoids interact with G protein-coupled cannabinoid 1 (CB1) receptors in the central nervous system, resulting in analgesic, euphoric, and anticonvulsive effects.

**Synonyms:** - CBD/THC - Cannabidiol mixture with Tetrahydrocannabinol - Cannabis-Based Oromucosal Spray GW-1000-02 - GW-1000 - GW-1000-02 - NABIXIMOLS - Sativex - THC and CBD Mixture