Primary Cutaneous Marginal Zone Lymphoproliferative Disorder

**Semantic type:** Neoplastic Process

**Definition:** A B-cell lymphoproliferative disorder that arises from the skin. It was previously known as primary cutaneous marginal zone lymphoma of mucosa-associated lymphoid tissue. Two subtypes are recognized: heavy chain class-switched primary cutaneous marginal zone lymphoproliferative disorder and IgM-positive primary cutaneous marginal zone lymphoproliferative disorder. The majority of cases are class-switched and predominantly IgG-positive.

**Synonyms:** - C-MALT - Cutaneous Immunocytoma - Marginal Zone B Cell Lymphoma of Skin - Marginal Zone B Cell Lymphoma of the Skin - PCMZL - Primary Cutaneous Marginal Zone B Cell Lymphoma of Mucosa-Associated Lymphoid Tissue - Primary Cutaneous Marginal Zone B-Cell Lymphoma of Mucosa-Associated Lymphoid Tissue - Primary Cutaneous Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue - SALT Lymphoma - SALT lymphoma - Skin-Associated Lymphoid Tissue Lymphoma - Skin-associated lymphoid tissue lymphoma