Pramiconazole

**Semantic type:** Pharmacologic Substance

**Definition:** An orally-available triazole antifungal drug for the treatment of acute skin and mucosal fungal infections. Pramiconazole has a very long half-life allowing for once a week dosing but may display erratic absorption and idiosyncratic liver toxicity similar to intraconazole and fluconazole.

**Synonyms:** - 1-{4-[4-(4-{[(2R,4S)-2-(2,4-difluorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-3-isopropylimidazolidin-2-one - Azoline - PRAMICONAZOLE