Fondaparinux

**Semantic type:** Pharmacologic Substance

**Definition:** A synthetic glucopyranoside with antithrombotic activity. Fondaparinux selectively binds to antithrombin III, thereby potentiating the innate neutralization of activated factor X (Factor Xa) by antithrombin. Neutralization of Factor Xa inhibits its activity and interrupts the blood coagulation cascade, thereby preventing thrombin formation and thrombus development.

**Synonyms:** - FONDAPARINUX - Natural Heparin Pentasaccharide - ORG 31540 - PENTA - SR 90107 - fondaparinux