BMPR1B wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human BMPR1B wild-type allele is located within 4q22-q24 and is approximately 397 kb in length. This allele, which encodes bone morphogenetic protein receptor type IB protein, plays a role in the regulation of signaling. Mutations in the gene are associated with both acromesomelic chondrodysplasia with genital anomalies and brachydactyly types A2 and C.

**Synonyms:** - ALK-6 - ALK6 - Bone Morphogenetic Protein Receptor, Type IB wt Allele - CDw293