Sodium Dichloroacetate

**Semantic type:** Pharmacologic Substance

**Definition:** The sodium salt of dichloroacetic acid with potential antineoplastic activity. Dichloroacetate ion inhibits pyruvate dehydrogenase kinase, resulting in the inhibition of glycolysis and a decrease in lactate production. This agent may stimulate apoptosis in cancer cells by restoring normal mitochondrial-induced apoptotic signaling.

**Synonyms:** - CPC 211 - Dichloroacetic Acid, Sodium Salt - SODIUM DICHLOROACETATE