E3 SUMO-Protein Ligase CBX4

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** E3 SUMO-protein ligase CBX4 (558 aa, ~61 kDa) is encoded by the human CBX4 gene. This soluble, nuclear protein plays a role in repressing the expression of genes through SUMOylation of lysine 119 of histone H2A.

**Synonyms:** - CBX4 - Chromobox Protein Homolog 4 - EC 2.3.2.- - Pc2 - Polycomb 2 Homolog - hPc2