Histone-Lysine N-Methyltransferase SETD2

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Histone-lysine methyltransferase SETD2 (2564 aa, ~288 kDa) is encoded by the human SETD2 gene. This soluble, nuclear protein may play a role in epigenetic chromatin modification, and activation of transcription by RNA polymerase II.

**Synonyms:** - EC 2.1.1.43 - HIF-1 - HIP-1 - Huntingtin Interacting Protein 1 - Huntingtin Yeast Partner B - Huntingtin-Binding Protein, 231-kD - Huntingtin-Interacting Protein 1 - Huntingtin-Interacting Protein B - Lysine N-Methyltransferase 3A - Protein-Lysine N-Methyltransferase SETD2 - SET Domain-Containing Protein 2 - SETD2 - hSET2 - p231HBP