Histone-Lysine N-Methyltransferase KMT5B

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Histone-lysine N-methyltransferase KMT5B (855 aa, ~99 kDa) is encoded by the human KMT5B gene. This protein may play a role in repression of transcription by RNA polymerase II, and in establishment of pericentric heterochromatin domains.

**Synonyms:** - EC 2.1.1.43 - H4-K20-HMTase SUV420H1 - Histone-Lysine N-Methyltransferase SUV420H1 - KMT5B - Lysine N-Methyltransferase 5B - Lysine-Specific Methyltransferase 5B - Su(Var)4-20 Homolog 1 - Suppressor of Variegation 4-20 Homolog 1 - Suv4-20h1