Histone-Lysine N-Methyltransferase SUV39H2

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Histone-lysine N-methyltransferase SUV39H2 (410 aa, ~47 kDa) is encoded by the human SUV39H2 gene. This soluble, nuclear protein plays a role in establishment of constitutive heterochromatin at pericentric and telomeric regions. Trimethylation of H3K9 is also required to direct DNA methylation at pericentric repeats.

**Synonyms:** - EC 2.1.1.43 - H3-K9-HMTase 2 - Lysine N-methyltransferase 1B - Su(var)3-9 homolog 2 - Suppressor of variegation 3-9 homolog 2 - Suv3-9h2