Rivoceranib Mesylate

**Semantic type:** Pharmacologic Substance

**Definition:** The mesylate salt of rivoceranib, an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities. Rivoceranib selectively binds to and inhibits vascular endothelial growth factor receptor 2, which may inhibit VEGF-stimulated endothelial cell migration and proliferation and decrease tumor microvessel density. In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases.

**Synonyms:** - Aitan - Apatinib Mesylate - RIVOCERANIB MESYLATE - YN 968D1 - YN-968D1 - YN968D1