Glisindamide

**Semantic type:** Pharmacologic Substance

**Definition:** A second-generation sulfonylurea with antihyperglycemic activity. Like other second-generation compounds, glisindamide exerts greater binding affinity to sulfonylurea receptor type 1 (SUR1) than the first-generation compounds and shows peroxisome proliferator-activated receptor gamma (PPARgamma) agonistic activity.

**Synonyms:** - 1-Cyclohexyl-3-((p-(2-(1-oxo-2- isoindolinecarboxamido)ethyl)phenyl)sulfonyl)urea - GLISINDAMIDE - HOE 036