BTK wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human BTK wild-type allele is located within Xq21.33-q22 and is approximately 37 kb in length. This allele, which encodes tyrosine-protein kinase BTK protein, plays a role in the mediation of signal transduction during B-cell development. Mutation of the gene is associated with X-linked agammaglobulinemia type 1.

**Synonyms:** - AGMX1 - AT - ATK - BPK - Bruton Agammaglobulinemia Tyrosine Kinase Gene - Bruton Tyrosine Kinase wt Allele - IMD1 - MGC126261 - MGC126262 - PSCTK1 - XLA